Mutations in the Primer Grip of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Impair Proviral DNA Synthesis and Virion Maturation
This report describes the effects of mutating highly conserved residues in the primer grip domain of human immunodeficiency virus type 1 reverse transcriptase (RT) on virus formation and infectivity. Among a series of RT mutant viruses, three (M230A, L234D, and W239A) were found to be noninfectious...
שמור ב:
| הוצא לאור ב: | J Virol |
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| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
1998
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110040/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9696874/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.9.7676-7680.1998 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
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