3′-Azido-3′-Deoxythymidine (AZT) Mediates Cross-Resistance to Nucleoside Analogs in the Case of AZT-Resistant Human Immunodeficiency Virus Type 1 Variants

Difficulties in deciphering the mechanisms of 3′-azido-3′-deoxythymidine (AZT)-resistance by human immunodeficiency virus type 1 (HIV-1) variants are due in part to an inability to reconstitute resistance in vitro using AZT-resistant reverse transcriptases. We decided to characterize mechanisms of A...

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Main Authors: Arts, Eric J., Quiñones-Mateu, Miguel E., Albright, Jamie L., Marois, James-Paul, Hough, Charles, Gu, Zhengxian, Wainberg, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Animal Viruses
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110035/
https://ncbi.nlm.nih.gov/pubmed/9573252
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