Measles Virus Spread and Pathogenesis in Genetically Modified Mice

Attenuated Edmonston measles virus (MV-Edm) is not pathogenic in standard mice. We show here that MV-Edm inoculated via the natural respiratory route has a limited propagation in the lungs of mice with a targeted mutation inactivating the alpha/beta interferon receptor. A high dose of MV-Edm adminis...

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Bibliographic Details
Main Authors: Mrkic, Branka, Pavlovic, Jovan, Rülicke, Thomas, Volpe, Pietro, Buchholz, Christian J., Hourcade, Dennis, Atkinson, John P., Aguzzi, Adriano, Cattaneo, Roberto
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109970/
https://ncbi.nlm.nih.gov/pubmed/9696838
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