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Measles Virus Spread and Pathogenesis in Genetically Modified Mice

Attenuated Edmonston measles virus (MV-Edm) is not pathogenic in standard mice. We show here that MV-Edm inoculated via the natural respiratory route has a limited propagation in the lungs of mice with a targeted mutation inactivating the alpha/beta interferon receptor. A high dose of MV-Edm adminis...

Ausführliche Beschreibung

Gespeichert in:
Veröffentlicht in:J Virol
Hauptverfasser: Mrkic, Branka, Pavlovic, Jovan, Rülicke, Thomas, Volpe, Pietro, Buchholz, Christian J., Hourcade, Dennis, Atkinson, John P., Aguzzi, Adriano, Cattaneo, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1998
Schlagworte:
Viral Pathogenesis and Immunity
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109970/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9696838/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.9.7420-7427.1998
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