Rescue of Defective Poliovirus RNA Replication by 3AB-Containing Precursor Polyproteins

This study demonstrates the in vitro complementation of an RNA replication-defective lesion in poliovirus RNA by providing a replicase/polymerase precursor polypeptide [P3(wt) {wild type}] in trans. The replication-defective mutation was a phenylalanine-to-histidine change (F69H) in the hydrophobic...

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Pubblicato in:	J Virol
Autori principali:	Towner, Jonathan S., Mazanet, Melissa M., Semler, Bert L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Animal Viruses
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9696813/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.9.7191-7200.1998
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