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Rescue of Defective Poliovirus RNA Replication by 3AB-Containing Precursor Polyproteins

This study demonstrates the in vitro complementation of an RNA replication-defective lesion in poliovirus RNA by providing a replicase/polymerase precursor polypeptide [P3(wt) {wild type}] in trans. The replication-defective mutation was a phenylalanine-to-histidine change (F69H) in the hydrophobic...

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Detalhes bibliográficos
Main Authors: Towner, Jonathan S., Mazanet, Melissa M., Semler, Bert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109941/
https://ncbi.nlm.nih.gov/pubmed/9696813
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