Identification of Persistent RNA-DNA Hybrid Structures within the Origin of Replication of Human Cytomegalovirus

Human cytomegalovirus (HCMV) lytic-phase DNA replication initiates at the cis-acting origin of replication, oriLyt. oriLyt is a structurally complex region containing repeat elements and transcription factor binding sites. We identified two site-specific alkali-labile regions within oriLyt which fla...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Prichard, Mark N., Jairath, Sanju, Penfold, Mark E. T., Jeor, Stephen St., Bohlman, Marlene C., Pari, Gregory S.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Animal Viruses
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109919/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9696791/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.9.6997-7004.1998
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