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Identification of Persistent RNA-DNA Hybrid Structures within the Origin of Replication of Human Cytomegalovirus

Human cytomegalovirus (HCMV) lytic-phase DNA replication initiates at the cis-acting origin of replication, oriLyt. oriLyt is a structurally complex region containing repeat elements and transcription factor binding sites. We identified two site-specific alkali-labile regions within oriLyt which fla...

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Bibliographic Details
Main Authors: Prichard, Mark N., Jairath, Sanju, Penfold, Mark E. T., Jeor, Stephen St., Bohlman, Marlene C., Pari, Gregory S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109919/
https://ncbi.nlm.nih.gov/pubmed/9696791
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