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Sequence Requirements for Removal of tRNA by an Isolated Human Immunodeficiency Virus Type 1 RNase H Domain

Retroviral reverse transcriptase-associated RNase H enzymes are responsible for degradation of viral RNA, including removal of the tRNA primer after plus-strand strong-stop synthesis and cleavage of the polypurine tract primer. These activities are required for the complex viral replication and resu...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Smith, Christine M., Leon, Oscar, Smith, Jeffrey S., Roth, Monica J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109889/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9658129/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.8.6805-6812.1998
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