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Sequence Requirements for Removal of tRNA by an Isolated Human Immunodeficiency Virus Type 1 RNase H Domain

Retroviral reverse transcriptase-associated RNase H enzymes are responsible for degradation of viral RNA, including removal of the tRNA primer after plus-strand strong-stop synthesis and cleavage of the polypurine tract primer. These activities are required for the complex viral replication and resu...

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Hlavní autoři: Smith, Christine M., Leon, Oscar, Smith, Jeffrey S., Roth, Monica J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC109889/
https://ncbi.nlm.nih.gov/pubmed/9658129
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