Actinomycin D Inhibits Human Immunodeficiency Virus Type 1 Minus-Strand Transfer in In Vitro and Endogenous Reverse Transcriptase Assays

In this report we demonstrate that human immunodeficiency virus type 1 (HIV-1) minus-strand transfer, assayed in vitro and in endogenous reactions, is greatly inhibited by actinomycin D. Previously we showed that HIV-1 nucleocapsid (NC) protein (a nucleic acid chaperone catalyzing nucleic acid rearr...

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Autores principales: Guo, Jianhui, Wu, Tiyun, Bess, Julian, Henderson, Louis E., Levin, Judith G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Animal Viruses
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC109878/
https://ncbi.nlm.nih.gov/pubmed/9658119
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