Actinomycin D Inhibits Human Immunodeficiency Virus Type 1 Minus-Strand Transfer in In Vitro and Endogenous Reverse Transcriptase Assays

In this report we demonstrate that human immunodeficiency virus type 1 (HIV-1) minus-strand transfer, assayed in vitro and in endogenous reactions, is greatly inhibited by actinomycin D. Previously we showed that HIV-1 nucleocapsid (NC) protein (a nucleic acid chaperone catalyzing nucleic acid rearr...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Guo, Jianhui, Wu, Tiyun, Bess, Julian, Henderson, Louis E., Levin, Judith G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Animal Viruses
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109878/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9658119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.8.6716-6724.1998
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