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Changing the Site of Initiation of Plus-Strand DNA Synthesis Inhibits the Subsequent Template Switch during Replication of a Hepadnavirus

Unique to hepadnavirus reverse transcription is the process of primer translocation, in which the RNA primer for the initiation of plus-strand DNA synthesis is generated at one site on its template, DR1, and is moved to a new site, DR2. For duck hepatitis B virus (DHBV), DR2 is located within 50 nuc...

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Autori principali: Loeb, Daniel D., Tian, Ru, Gulya, Karolyn J., Qualey, Amy E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109832/
https://ncbi.nlm.nih.gov/pubmed/9658101
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