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Mutations within DR2 independently reduce the amount of both minus- and plus-strand DNA synthesized during duck hepatitis B virus replication.

The initial aim of this study was to examine the role of complementarity between the plus-strand primer and the minus-strand DNA template for translocation of the plus-strand primer in hepadnaviral replication. We show that when a 5-nucleotide substitution was placed in either DR1 or DR2, translocat...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Loeb, D D, Tian, R, Gulya, K J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190963/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8970995/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.12.8684-8690.1996
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