Loss of Viral Fitness Associated with Multiple Gag and Gag-Pol Processing Defects in Human Immunodeficiency Virus Type 1 Variants Selected for Resistance to Protease Inhibitors In Vivo

We examined the viral replicative capacity and protease-mediated processing of Gag and Gag-Pol precursors of human immunodeficiency virus (HIV) variants selected for resistance to protease inhibitors. We compared recombinant viruses carrying plasma HIV RNA protease sequences obtained from five patie...

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Main Authors: Zennou, Véronique, Mammano, Fabrizio, Paulous, Sylvie, Mathez, Dominique, Clavel, François
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
Assuntos:
Animal Viruses
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC109806/
https://ncbi.nlm.nih.gov/pubmed/9525657
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