The Proteolytic Cleavage of Human Immunodeficiency Virus Type 1 Nef Does Not Correlate with Its Ability To Stimulate Virion Infectivity

The Nef protein of human immunodeficiency virus type 1 (HIV-1) promotes virion infectivity through mechanisms that are yet ill defined. Some Nef is incorporated into particles, where it is cleaved by the viral protease between amino acids 57 and 58. The functional significance of this event, which l...

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Pubblicato in:	J Virol
Autori principali:	Chen, Yen-Liang, Trono, Didier, Camaur, Diana
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Animal Viruses
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109778/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525644/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.4.3178-3184.1998
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