Plasma Membrane-Targeted Raf Kinase Activates NF-κB and Human Immunodeficiency Virus Type 1 Replication in T Lymphocytes

Increasing evidence points to a role of the mitogenic Ras/Raf/MEK/ERK signaling cascade in regulation of human immunodeficiency virus type 1 (HIV-1) gene expression. Stimulation of elements of this pathway leads to transactivation of the HIV-1 promoter. In particular, the NF-κB motif in the HIV long...

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Détails bibliographiques
Auteurs principaux: Flory, Egbert, Weber, Christoph K., Chen, Peifeng, Hoffmeyer, Angelika, Jassoy, Christian, Rapp, Ulf R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109723/
https://ncbi.nlm.nih.gov/pubmed/9525598
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