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Scaffold Attachment Region-Mediated Enhancement of Retroviral Vector Expression in Primary T Cells

We have studied retroviral transgene expression in primary human lymphocytes. Our data demonstrate that transgene expression is high in activated primary CD4(+) T cells but significantly decreased in mitotically quiescent cells. Incorporation of a DNA fragment from the scaffold attachment region (SA...

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Main Authors: Agarwal, Manju, Austin, Timothy W., Morel, Franck, Chen, Jingyi, Böhnlein, Ernst, Plavec, Ivan
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1998
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109594/
https://ncbi.nlm.nih.gov/pubmed/9557654
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