Application of a Fas Ligand Encoding a Recombinant Adenovirus Vector for Prolongation of Transgene Expression

An adenovirus vector encoding murine Fas ligand (mFasL) under an inducible control was derived. In vivo ectopic expression of mFasL in murine livers induced an inflammatory cellular infiltration. Furthermore, ectopic expression of mFasL by myocytes did not allow prolonged vector-mediated transgene e...

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Hlavní autoři: Zhang, Huang-Ge, Bilbao, Guadalupe, Zhou, Tong, Contreras, Juan Luis, Gómez-Navarro, Jesús, Feng, Meizhen, Saito, Izumu, Mountz, John D., Curiel, David T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Gene Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC109549/
https://ncbi.nlm.nih.gov/pubmed/9499110
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