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Immune Response to Recombinant Capsid Proteins of Adenovirus in Humans: Antifiber and Anti-Penton Base Antibodies Have a Synergistic Effect on Neutralizing Activity

Replication-deficient adenovirus used in humans for gene therapy induces a strong immune response to the vector, resulting in transient recombinant protein expression and the blocking of gene transfer upon a second administration. Therefore, in this study we examined in detail the capsid-specific hu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gahéry-Ségard, Hanne, Farace, Françoise, Godfrin, Dominique, Gaston, Jesintha, Lengagne, Renée, Tursz, Thomas, Boulanger, Pierre, Guillet, Jean-Gérard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC109538/
https://ncbi.nlm.nih.gov/pubmed/9499099
Tagiau: Ychwanegu Tag
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