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Analysis of Host Range Restriction Determinants in the Rabbit Model: Comparison of Homologous and Heterologous Rotavirus Infections

The main limitation of both the rabbit and mouse models of rotavirus infection is that human rotavirus (HRV) strains do not replicate efficiently in either animal. The identification of individual genes necessary for conferring replication competence in a heterologous host is important to an underst...

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Bibliographic Details
Main Authors: Ciarlet, Max, Estes, Mary K., Barone, Christopher, Ramig, Robert F., Conner, Margaret E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109534/
https://ncbi.nlm.nih.gov/pubmed/9499095
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