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An Endonuclease Switching Mechanism in the Virion RNA and cRNA Promoters of Thogoto Orthomyxovirus

An in vitro assay was developed to investigate endonuclease activity of Thogoto virus, a tick-borne orthomyxovirus. Endonuclease activity relied on an interaction between the 3′ and 5′ termini of virion RNA (vRNA) and not those of cRNA. Evidence was obtained that cap structures are cleaved directly...

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Detalles Bibliográficos
Main Authors: Leahy, Michael B., Dessens, Johannes T., Pritlove, David C., Nuttall, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC109529/
https://ncbi.nlm.nih.gov/pubmed/9499090
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