Inducible Overexpression of a Toxic Protein by an Adenovirus Vector with a Tetracycline-Regulatable Expression Cassette

We have constructed two new adenovirus expression cassettes that expand both the range of genes which can be expressed with adenovirus vectors (AdV) and the range of cells in which high-level expression can be attained. By inclusion of a tetracycline-regulated promoter in the transfer vector pAdTR5,...

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Autori principali: Massie, Bernard, Couture, France, Lamoureux, Linda, Mosser, Dick D., Guilbault, Claire, Jolicoeur, Pierre, Bélanger, François, Langelier, Yves
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
Soggetti:
Gene Therapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109527/
https://ncbi.nlm.nih.gov/pubmed/9499088
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