CD4 Glycoprotein Degradation Induced by Human Immunodeficiency Virus Type 1 Vpu Protein Requires the Function of Proteasomes and the Ubiquitin-Conjugating Pathway

The human immunodeficiency virus type 1 (HIV-1) vpu gene encodes a type I anchored integral membrane phosphoprotein with two independent functions. First, it regulates virus release from a post-endoplasmic reticulum (ER) compartment by an ion channel activity mediated by its transmembrane anchor. Se...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Schubert, Ulrich, Antón, Luis C., Bačík, Igor, Cox, Josephine H., Bour, Stéphane, Bennink, Jack R., Orlowski, Marian, Strebel, Klaus, Yewdell, Jonathan W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109526/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9499087/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.3.2280-2288.1998
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