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Signal Peptidase Cleavage at the Flavivirus C-prM Junction: Dependence on the Viral NS2B-3 Protease for Efficient Processing Requires Determinants in C, the Signal Peptide, and prM

Signal peptidase cleavage at the C-prM junction in the flavivirus structural polyprotein is inefficient in the absence of the cytoplasmic viral protease, which catalyzes cleavage at the COOH terminus of the C protein. The signal peptidase cleavage occurs efficiently in circumstances where the C prot...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Stocks, C. E., Lobigs, M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109509/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9499070/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.3.2141-2149.1998
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