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Upregulation of signalase processing and induction of prM-E secretion by the flavivirus NS2B-NS3 protease: roles of protease components.

Recently, we have shown that the ability of the flavivirus NS2B-NS3 protease complex to promote efficient signalase processing of the C-prM precursor, as well as secretion of prM and E, does not appear to depend strictly on cleavage of the precursor at its Lys-Arg-Gly dibasic site by the protease. W...

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Udgivet i:J Virol
Principais autores: Yamshchikov, V F, Trent, D W, Compans, R W
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151825/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4364-4371.1997
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