Competition for DNA Binding Sites between the Short and Long Forms of E2 Dimers Underlies Repression in Bovine Papillomavirus Type 1 DNA Replication Control

Papillomaviruses establish a long-term latency in vivo by maintaining their genomes as nuclear plasmids in proliferating cells. Bovine papillomavirus type 1 encodes two proteins required for viral DNA replication: the helicase E1 and the positive regulator E2. The homodimeric E2 is known to cooperat...

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Bibliographic Details
Main Authors: Lim, Daniel A., Gossen, Manfred, Lehman, Chris W., Botchan, Michael R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Animal Viruses
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109485/
https://ncbi.nlm.nih.gov/pubmed/9499046
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