Neutralization Sensitivity of Human Immunodeficiency Virus Type 1 Primary Isolates to Antibodies and CD4-Based Reagents Is Independent of Coreceptor Usage

We have investigated whether the identity of the coreceptor (CCR5, CXCR4, or both) used by primary human immunodeficiency virus type 1 (HIV-1) isolates to enter CD4(+) cells influences the sensitivity of these isolates to neutralization by monoclonal antibodies and CD4-based agents. Coreceptor usage...

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Auteurs principaux: Trkola, Alexandra, Ketas, Tom, KewalRamani, Vineet N., Endorf, Fred, Binley, James M., Katinger, Hermann, Robinson, Jim, Littman, Dan R., Moore, John P.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109478/
https://ncbi.nlm.nih.gov/pubmed/9499039
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