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Protease Cleavage of Reovirus Capsid Protein μ1/μ1C Is Blocked by Alkyl Sulfate Detergents, Yielding a New Type of Infectious Subvirion Particle

Mammalian reovirus virions undergo partial disassembly of the outer capsid upon exposure to proteases in vitro, producing infectious subvirion particles (ISVPs) that lack protein ς3 and contain protein μ1/μ1C as endoprotease-generated fragments μ1δ/δ and φ. ISVPs are thought to be required for two e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chandran, Kartik, Nibert, Max L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109396/
https://ncbi.nlm.nih.gov/pubmed/9420247
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