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Defective Growth Correlates with Reduced Accumulation of a Viral DNA Replication Protein after Low-Multiplicity Infection by a Human Cytomegalovirus ie1 Mutant

To investigate the importance of the IE1 p72 regulatory protein during human cytomegalovirus replication, a recombinant virus unable to synthesize IE1 p72 was constructed. The Towne strain mutant CR208 lacked exon 4 of the major immediate-early gene and was isolated and complemented in an IE1-expres...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Greaves, Richard F., Mocarski, Edward S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109384/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420235/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.1.366-379.1998
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