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Defective Growth Correlates with Reduced Accumulation of a Viral DNA Replication Protein after Low-Multiplicity Infection by a Human Cytomegalovirus ie1 Mutant

To investigate the importance of the IE1 p72 regulatory protein during human cytomegalovirus replication, a recombinant virus unable to synthesize IE1 p72 was constructed. The Towne strain mutant CR208 lacked exon 4 of the major immediate-early gene and was isolated and complemented in an IE1-expres...

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Vydáno v:J Virol
Hlavní autoři: Greaves, Richard F., Mocarski, Edward S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109384/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420235/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.1.366-379.1998
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