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Characterization of Replication-Competent Hepatitis A Virus Constructs Containing Insertions at the N Terminus of the Polyprotein

To determine whether hepatitis A virus (HAV) could tolerate the insertion of exogenous sequences, we constructed full-length HAV cDNAs containing in-frame insertions at the N terminus of the polyprotein and transfected the derived T7 RNA polymerase in vitro transcripts into FRhK-4 cells. Replication...

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Bibliografske podrobnosti
izdano v:J Virol
Principais autores: Zhang, Yuan, Kaplan, Gerardo G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1998
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109382/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420233/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.1.349-357.1998
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