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Cells with High Cyclophilin A Content Support Replication of Human Immunodeficiency Virus Type 1 Gag Mutants with Decreased Ability To Incorporate Cyclophilin A

Gag polyprotein-mediated incorporation of cellular cyclophilin A (CyPA) into virions is essential for the formation of infectious human immunodeficiency virus type 1 (HIV-1) virions. Either a point mutation in Gag (P222A) or drugs which bind CyPA decrease virion incorporation of CyPA and interfere w...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:J Virol
Ngā kaituhi matua: Ackerson, Bradley, Rey, Osvaldo, Canon, Jude, Krogstad, Paul
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Microbiology (ASM) 1998
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109377/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420228/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.1.303-308.1998
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