Cells with High Cyclophilin A Content Support Replication of Human Immunodeficiency Virus Type 1 Gag Mutants with Decreased Ability To Incorporate Cyclophilin A

Gag polyprotein-mediated incorporation of cellular cyclophilin A (CyPA) into virions is essential for the formation of infectious human immunodeficiency virus type 1 (HIV-1) virions. Either a point mutation in Gag (P222A) or drugs which bind CyPA decrease virion incorporation of CyPA and interfere w...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ackerson, Bradley, Rey, Osvaldo, Canon, Jude, Krogstad, Paul
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109377/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.1.303-308.1998
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