Amino-Terminal Substitutions in the CCR5 Coreceptor Impair gp120 Binding and Human Immunodeficiency Virus Type 1 Entry

The CC-chemokine receptor CCR5 is required for the efficient fusion of macrophage (M)-tropic human immunodeficiency virus type 1 (HIV-1) strains with the plasma membrane of CD4(+) cells and interacts directly with the viral surface glycoprotein gp120. Although receptor chimera studies have provided...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Dragic, Tatjana, Trkola, Alexandra, Lin, Steven W., Nagashima, Kirsten A., Kajumo, Francis, Zhao, Lu, Olson, William C., Wu, Lijun, Mackay, Charles R., Allaway, Graham P., Sakmar, Thomas P., Moore, John P., Maddon, Paul J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109374/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420225/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.1.279-285.1998
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