Sequences within the Herpesvirus-Conserved pac1 and pac2 Motifs Are Required for Cleavage and Packaging of the Murine Cytomegalovirus Genome

The DNA sequence motifs pac1 [an A-rich region flanked by poly(C) runs] and pac2 (CGCGGCG near an A-rich region) are conserved near herpesvirus genomic termini and are believed to mediate cleavage of genomes from replicative concatemers. To determine their importance in the cleavage process, we cons...

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Bibliografiske detaljer
Main Authors: McVoy, Michael A., Nixon, Daniel E., Adler, Stuart P., Mocarski, Edward S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Animal Viruses
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109348/
https://ncbi.nlm.nih.gov/pubmed/9420199
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