Sequences within the Herpesvirus-Conserved pac1 and pac2 Motifs Are Required for Cleavage and Packaging of the Murine Cytomegalovirus Genome

The DNA sequence motifs pac1 [an A-rich region flanked by poly(C) runs] and pac2 (CGCGGCG near an A-rich region) are conserved near herpesvirus genomic termini and are believed to mediate cleavage of genomes from replicative concatemers. To determine their importance in the cleavage process, we cons...

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Pubblicato in:	J Virol
Autori principali:	McVoy, Michael A., Nixon, Daniel E., Adler, Stuart P., Mocarski, Edward S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Animal Viruses
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109348/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420199/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.1.48-56.1998
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