Activation of the Ras/Mitogen-Activated Protein Kinase Pathway by Kinase-Defective Epidermal Growth Factor Receptors Results in Cell Survival but Not Proliferation

Signalling by the epidermal growth factor (EGF) receptor (EGFR) has been studied intensively, but for most cell types the analysis is complicated by the fact that EGFR not only homodimerizes but can also form heterodimers with other EGFR family members. Heterodimerization is a particular problem in...

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Detalles Bibliográficos
Main Authors: Walker, Francesca, Kato, Akiko, Gonez, L. Jorge, Hibbs, Margaret L., Pouliot, Normand, Levitzki, Alexander, Burgess, Antony W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC109301/
https://ncbi.nlm.nih.gov/pubmed/9819406
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