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ETO, a Target of t(8;21) in Acute Leukemia, Interacts with the N-CoR and mSin3 Corepressors

t(8;21) is one of the most frequent translocations associated with acute myeloid leukemia. It produces a chimeric protein, acute myeloid leukemia-1 (AML-1)–eight-twenty-one (ETO), that contains the amino-terminal DNA binding domain of the AML-1 transcriptional regulator fused to nearly all of ETO. H...

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Autori principali: Lutterbach, Bart, Westendorf, Jennifer J., Linggi, Bryan, Patten, Andrea, Moniwa, Mariko, Davie, James R., Huynh, Khanh D., Bardwell, Vivian J., Lavinsky, Robert M., Rosenfeld, Michael G., Glass, Christopher, Seto, Edward, Hiebert, Scott W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109299/
https://ncbi.nlm.nih.gov/pubmed/9819404
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