Nucleophosmin-Anaplastic Lymphoma Kinase of Large-Cell Anaplastic Lymphoma Is a Constitutively Active Tyrosine Kinase That Utilizes Phospholipase C-γ To Mediate Its Mitogenicity

Large-cell anaplastic lymphoma is a subtype of non-Hodgkin’s lymphoma characterized by the expression of CD30. More than half of these lymphomas have a chromosomal translocation, t(2;5), that leads to the expression of a hybrid protein comprised of the nucleolar phosphoprotein nucleophosmin (NPM) an...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Bai, Ren-Yuan, Dieter, Peter, Peschel, Christian, Morris, Stephan W., Duyster, Justus
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1998
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109278/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9819383/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.12.6951
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