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Nucleophosmin-Anaplastic Lymphoma Kinase of Large-Cell Anaplastic Lymphoma Is a Constitutively Active Tyrosine Kinase That Utilizes Phospholipase C-γ To Mediate Its Mitogenicity

Large-cell anaplastic lymphoma is a subtype of non-Hodgkin’s lymphoma characterized by the expression of CD30. More than half of these lymphomas have a chromosomal translocation, t(2;5), that leads to the expression of a hybrid protein comprised of the nucleolar phosphoprotein nucleophosmin (NPM) an...

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Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Bai, Ren-Yuan, Dieter, Peter, Peschel, Christian, Morris, Stephan W., Duyster, Justus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109278/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9819383/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.12.6951
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