Cytoplasmic Dynein Intermediate-Chain Isoforms with Different Targeting Properties Created by Tissue-Specific Alternative Splicing

The intermediate chains (ICs) are the subunits of the cytoplasmic dynein that provide binding of the complex to cargo organelles through interaction of their N termini with dynactin. We present evidence that in Drosophila, the IC subunits are represented by at least 10 structural isoforms, created b...

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Autors principals: Nurminsky, Dmitry I., Nurminskaya, Maria V., Benevolenskaya, Elizaveta V., Shevelyov, Yury Y., Hartl, Daniel L., Gvozdev, Vladimir A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Cell and Organelle Structure and Assembly
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC109265/
https://ncbi.nlm.nih.gov/pubmed/9774695
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