Targeted Inactivation of Mouse RAD52 Reduces Homologous Recombination but Not Resistance to Ionizing Radiation

The RAD52 epistasis group is required for recombinational repair of double-strand breaks (DSBs) and shows strong evolutionary conservation. In Saccharomyces cerevisiae, RAD52 is one of the key members in this pathway. Strains with mutations in this gene show strong hypersensitivity to DNA-damaging a...

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Autores principales: Rijkers, Tonnie, Van Den Ouweland, Jody, Morolli, Bruno, Rolink, Anton G., Baarends, Willy M., Van Sloun, Petra P. H., Lohman, Paul H. M., Pastink, Albert
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC109228/
https://ncbi.nlm.nih.gov/pubmed/9774658
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