Targeted Inactivation of Mouse RAD52 Reduces Homologous Recombination but Not Resistance to Ionizing Radiation

The RAD52 epistasis group is required for recombinational repair of double-strand breaks (DSBs) and shows strong evolutionary conservation. In Saccharomyces cerevisiae, RAD52 is one of the key members in this pathway. Strains with mutations in this gene show strong hypersensitivity to DNA-damaging a...

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Main Authors: Rijkers, Tonnie, Van Den Ouweland, Jody, Morolli, Bruno, Rolink, Anton G., Baarends, Willy M., Van Sloun, Petra P. H., Lohman, Paul H. M., Pastink, Albert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109228/
https://ncbi.nlm.nih.gov/pubmed/9774658
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