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DNA-tension dependence of restriction enzyme activity reveals mechanochemical properties of the reaction pathway
Type II restriction endonucleases protect bacteria against phage infections by cleaving recognition sites on foreign double-stranded DNA (dsDNA) with extraordinary specificity. This capability arises primarily from large conformational changes in enzyme and/or DNA upon target sequence recognition. I...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1092278/ https://ncbi.nlm.nih.gov/pubmed/15886396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki565 |
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