Ectopic Expression of cdc2/cdc28 Kinase Subunit Homo sapiens 1 Uncouples Cyclin B Metabolism from the Mitotic Spindle Cell Cycle Checkpoint

Primary human fibroblasts arrest growth in response to the inhibition of mitosis by mitotic spindle-depolymerizing drugs. We show that the mechanism of mitotic arrest is transient and implicates a decrease in the expression of cdc2/cdc28 kinase subunit Homo sapiens 1 (CKsHs1) and a delay in the meta...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Hixon, Mary L., Flores, Ana I., Wagner, Mark W., Gualberto, Antonio
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1998
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109209/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6224
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