Two Independent Internal Ribosome Entry Sites Are Involved in Translation Initiation of Vascular Endothelial Growth Factor mRNA

The mRNA of vascular endothelial growth factor (VEGF), the major angiogenic growth factor, contains an unusually long (1,038 nucleotides) and structured 5′ untranslated region (UTR). According to the classical translation initiation model of ribosome scanning, such a 5′ UTR is expected to be a stron...

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Main Authors: Huez, Isabelle, Créancier, Laurent, Audigier, Sylvie, Gensac, Marie-Claire, Prats, Anne-Catherine, Prats, Hervé
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
Assuntos:
Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC109205/
https://ncbi.nlm.nih.gov/pubmed/9774635
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