Two Independent Internal Ribosome Entry Sites Are Involved in Translation Initiation of Vascular Endothelial Growth Factor mRNA

The mRNA of vascular endothelial growth factor (VEGF), the major angiogenic growth factor, contains an unusually long (1,038 nucleotides) and structured 5′ untranslated region (UTR). According to the classical translation initiation model of ribosome scanning, such a 5′ UTR is expected to be a stron...

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Bibliographische Detailangaben
Hauptverfasser: Huez, Isabelle, Créancier, Laurent, Audigier, Sylvie, Gensac, Marie-Claire, Prats, Anne-Catherine, Prats, Hervé
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109205/
https://ncbi.nlm.nih.gov/pubmed/9774635
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