Nuclear Localization of the Nipah Virus W Protein Allows for Inhibition of both Virus- and Toll-Like Receptor 3-Triggered Signaling Pathways

The Nipah virus V and W proteins, which are encoded by the P gene via RNA editing, have a common N-terminal domain but unique C-terminal domains. They localize to the cytoplasm and nucleus, respectively, and have both been shown to function as inhibitors of JAK/STAT signaling. Here we report that V...

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Bibliographic Details
Main Authors: Shaw, Megan L., Cardenas, Washington B., Zamarin, Dmitriy, Palese, Peter, Basler, Christopher F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2005
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091709/
https://ncbi.nlm.nih.gov/pubmed/15857993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6078-6088.2005
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