Role of Genes That Modulate Host Immune Responses in the Immunogenicity and Pathogenicity of Vaccinia Virus

Poxvirus vaccine vectors, although capable of eliciting potent immune responses, pose serious health risks in immunosuppressed individuals. We therefore constructed five novel recombinant vaccinia virus vectors which contained overlapping deletions of coding regions for the B5R, B8R, B12R, B13R, B14...

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Detalhes bibliográficos
Main Authors: Jackson, Shawn S., Ilyinskii, Petr, Philippon, Valérie, Gritz, Linda, Yafal, Alicia Gómez, Zinnack, Kimberly, Beaudry, Kristin R., Manson, Kelledy H., Lifton, Michelle A., Kuroda, Marcelo J., Letvin, Norman L., Mazzara, Gail P., Panicali, Dennis L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091706/
https://ncbi.nlm.nih.gov/pubmed/15858042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6554-6559.2005
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